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Arimidex (anastrozole) was the first selective aromatase inhibitor used in bodybuilding and is still the most popular estrogen control agent. It is a widely available agent both in liquid form and tablets for oral use. Dosage is usually 0.25, 0.5, or 1.0 mg at a time, with a frequency of once a day or two days.
Estradiol is the strongest form of estrogen, it is produced in the body during the process of testosterone aromatization. This is done via the aromatase enzyme. Since certain levels of estradiol are required for men, some conversion of testosterone to estradiol is needed. In both cases, however, effective aromatase inhibition can provide significant benefits.
First of all, when the anabolic steroid increases the aromatization very much during the cycle, the steroid level has no control of the aromatase enzyme, the conversion to estradiol becomes excessive. With high estradiol levels it can cause gynecomastia, water retention, depression, and / or loss of libido. It can also cause that it is difficult to maintain the acquired muscle mass.
And secondly, some people have excessive estradiol levels, even if they are not on the cycle with anabolic steroids. In this way, we work to reduce their natural testosterone production, and can also cause the above adverse side effects.
Arimidex is perfect for solving the above problems. With the correct dosage, the level of free estradiol can be brought in quite accurately within the desired range. If you don’t use anabolic steroids, for most men I recommend around 20-29 pg / ml for the best effect on mood, performance, libido and long-term health and provide the excellent benefits of natural testosterone production. During the steroid cycle, growth may be slightly higher because high levels of androgen work to combat the negative effects of estradiol. Sometimes the level is intentionally higher because it can improve by improving performance. Still, I recommend, even during a strong anabolic cycle, estradiol levels should be limited to slightly more than about 40 pg / mL. This is usually required by aromatase inhibitors such as Arimidex if the dosage of steroid aromatization is high.
The most aromatize steroids such as testosterone, methyltestosterone and Dianabol, but also Deca (nandrolone). Equipoise (Boldenone) also aromatizes, but to a lesser extent.
Most medical studies have shown that the effect of Arimidex on men who used it at a dose of 1 mg / day, and this dose is rather optimal, judging by the effects of estradiol levels. However, the real world is used for both steroid cycle and optimization of hormone levels generally at a lower dose of 0.25 mg every other day to about 0.5 mg / day. And generally 0.5 mg every other day is the starting point for the steroid cycle, and half is taken to optimize the hormone if there is a high estrogen problem.
An overdose of Arimidex leads to abnormally low estradiol levels and typical side effects for it are arthralgia, decreased libido, and / or gastrointestinal insufficiency. The first two are directly caused by low estradiol. If these effects occur, the dose should be reduced. The effect on the gastrointestinal tract appears as a side effect of Arimidex itself, and if it occurs I recommend switching to letrozole as an alternative choice of inibitor aromatase.
Anastrozole has a half-life of about two days. For this reason, when used systematically in a cycle, in connection with taking a dose of Arimidex, the user will have in his system not only the dose that he just took now, but also for about another two days, “because arimidex is still in his body .
Instead of waiting a few weeks for buildup, it is recommended to concentrate Arimidex. This is done by taking the first dose not only of regular consumption. For example, if you intend to take 0.5 mg every other day, it will be an additional 0.5 mg. The secondary dose would therefore be 1.0 mg. This is only taken on the first day of use. Thanks to this method, proper action is achieved almost immediately.
Controversy in the use of Arimidex is in PCT, which is a popular sight. Some say fluctuations in estradiol levels are abnormally low in PCT to stimulate testosterone production.
Arimidex is better than letrozole. The drug can be effectively used to control aromatase. The choice between them can only be made based on personal preferences, experience and availability.